When plants are under attack by pathogens such as bacteria or fungi they produce a phytoalexin. Resveratrol is one such compound and is commonly found in the skin of red grapes and in many other foodstuffs. It is currently marketed as one of many anti aging products.

It is still being researched and explored but scientists are very optimistic about the health properties associated with this unique nutrient.

Japanese Knotweed was the first know source of resveratrol. It can balance the body hormones and also counteracts aging spots and also triggers collagen production.

Resveratrol interferes with all three stages of carcinogenesis ” initiation, promotion and progression. It has been found to induce cell cycle arrest when added to cancer cells grown in culture also it has been found to inhibit proliferation and induce apoptosis in a number of cancer cell lines.

In vitro resveratrol interacts with multiple molecular targets and has positive effects on the cells of breast, skin, gastric, colon, esophageal, prostate, pancreatic cancer, and leukemia. The strongest evidence of anti-cancer action of resveratrol exists for tumors it can come into direct contact with, such as skin and gastrointestinal tract tumors. For other cancers, the evidence is uncertain, even if massive doses of resveratrol are used.

Resveratrol was reported effective against neuronal cell dysfunction and cell death, and in theory could help against diseases such as Huntington’s disease and Alzheimer’s disease. Again, this has not yet been tested in humans for any disease.

Researchers at the Weill Medical College of Cornell University reported that dietary supplementation with resveratrol significantly reduced plaque formation in animal brains, a component of Alzheimer and other Neurodegenerative diseases. In humans it is theorized that oral doses of resveratrol may reduce beta amyloid plaque associated with aging changes in the brain.

Aggregation of platelets is one of the first steps in the formation of a blood clot that can block a coronary or cerebral artery, resulting in a stroke. Resveratrol has been found to inhibit platelet aggregation in vitro.

Resveratrol appear to mimic several of the biochemical effects of calorie restriction. The sirt-1 gene activates a critical component of calorie restriction in mammals and promotes fat metabolization. There is evidence that resveratrol may be a calorie restriction mimetic, a compound that mimics the effects of calorie restriction by targeting metabolic and stress response pathways affected by calorie restriction, but without restricting caloric intake, which may be helpful in promoting a longer lifespan.

The lifespan of mice on a high-calorie diet including resveratrol was extended such that their lifespan was similar to that of mice fed a standard diet a recent study reported.

Resveratrol effectively scavenges (neutralizes) free radicals and other oxidants.

It is also claimed that this antioxidant can boost stamina, reduce lung inflammation stemming from chronic pulmonary disease, and help stave off cancer. A recent 60 minutes episode highlighted research which suggests that resveratrol can delay the aging process and prevent many gerontological diseases.

In detail this natural substance is being trialed against,

Free Radicals & Dangerous Toxins, Carcinogens of all types, Heart Disease, Stroke Risk, Cellular Level dysfunction, Brain and cell degeneration, and Lactic Acid Buildup.

And Promoting ,

Good Cholesterol, Natural Energy and Metabolic Rate.

As a food supplement resveratrol can be take orally, with a recommended dose of two capsules per day depending on the manufacturer.

Note: It is important to keep in mind that many of the biological activities discussed above were observed in cells cultured in the presence of resveratrol at higher concentrations than those likely to be achieved in humans consuming resveratrol orally.

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